DESCRIPTION
Modvigil 200 mg is a medication containing Modafinil, a wakefulness promoting agent used to treat Narcolepsy, Shift worker Sleep disorder and Sleep apnea. It typically takes 30 to 60 minutes to start working and the duration of action is around 10 to 12 hours. Modafinil is a non-amphetamine Central nervous system stimulant with wakefulness-promoting properties.Â
How does Modvigil 200 mg work?
Modvigil is an atypical dopamine reuptake inhibitor. It blocks the dopamine transporter and also prevents the reabsorption of dopamine into the neurons and thus it leads to increased focus, alertness. Modafinil also stimulates the orexin-hypocretin system in the hypothalamus which triggers the release of histamine, a neurotransmitter that dictates your sleep-wake cycle. The medication increases brain processing speed and fights fatigue by increasing the levels of excitatory glutamate and down-regulating inhibitory GABA. It also increases the levels of norepinephrine which contributes to overall arousal and vigilance.Â
ADDITIONAL INFORMATION
Key Features
| About Modvigil 200 mg | |
| Drug class: Central Nervous system Stimulant | |
| Sub class:Â Â Non-amphetamine wake-promoting agent |
| Product details | |
| Active Ingredient | Modafinil |
| Inactive Ingredients | Lactose Monohydrate
Microcrystalline cellulose Croscarmellose sodium Povidone Magnesium stearate Pregelatinized starch |
| Packaging type | Blister |
| Pack size | 10*10 |
| Dosage | 200 mg |
| Used for | Excessive sleep disorder |
| Onset of action | 30 to 60 minutes |
| Duration of action | 10 to 12 hours |
| Manufacturer | Sun Pharmaceuticals Pvt Ltd |
| Shelf life | 24 months after the manufacturing date |
| Storage | Store at room temperature away from sunlight and moisture |
USAGE
Modvigil 200 mg is used medically for excessive sleep disorders like Narcolepsy, Shift Worker Sleep Disorder (SWSD) and Obstructive Sleep Apnea (OSA).Â
It is also used off-label for Attention Deficit Hyperactivity Disorder (ADHD), Fatigue Management, Cognitive enhancement and chronic fatigue.Â
DOSAGE
Usual adult doses for excessive sleep disorders is listed below:
- Narcolepsy: The usual recommended dosage for Narcolepsy is 200 mg orally once a day.Â
- Obstructive Sleep apnea: 200 mg once per dayÂ
- Shift Worker Sleep Disorder: 200 mg one hour before the night shift begins.
Always follow the dosage prescribed by the healthcare advisor.Â
SIDE EFFECTS
Very common (usually affecting more than 10% of users):
- Headache
Common (affecting 1% to 10% of users):
- Anxiety
- Nervousness
- Insomnia
- Depression
- Nausea
- Diarrhea
- Dry mouth
- Indigestion
- Decreased appetite
- Runny or stuffy nose
- Muscle stiffness
Serious/ Rare risks:
- Hypertension
- Increased palpitations
- Chest pain
- Swelling of face, tongue, lipsÂ
- Difficulty in breathing
- Severe skin reactions
- Aggression
- Hallucinations
Interactions
Avoid or do not use Modafinil with the following medications:
- Amphetamine or dextroamphetamine
- Pemoline (CNS Stimulant)
- MAOIs like Phenelzine (sold as Nardil), Tranylcypromine (sold as Parnate) and Isocarboxazid (sold as Marplan)
- Procarbazine
Modafinil might also interact with the following:
- Antifungal medications such as Itraconazole, Ketoconazole
- Barbiturates like phenobarbital
- Carbamazepine
- Diazepam
- Phenytoin
- Cyclosporine
- Anticoagulants like warfarin
- Beta blockers like propranolol
It can also have an interaction with dietary compounds like grapefruit or grapefruit juice, alcohol and caffeine.Â
Precautions & Warnings
- Do not use the medication if you are hypersensitive to modafinil or any other component of the medication.Â
- Inform your physician if you are pregnant, planning to get pregnant or breastfeeding.Â
- Modafinil has the potential for abuse and dependency and thus it should be used with caution.Â
- Use with extreme caution if you have a history of depression, mania or psychosis.Â
- Do not self-administer or exceed the limit of prescribed dosage.Â
- Do not drive or use heavy machineries until you know how the medication works for you.Â
- Avoid excessive intake of caffeine e.g. coffee, tea, soda or chocolates
CONCLUSION
Modvigil 200 mg is a medication that consists of 200 mg of Modafinil, a CNS stimulant. It is used for the treatment of excessive sleep disorders like Narcolepsy, Shift Worker Sleep Disorder and Obstructive Sleep Apnea. There are some side effects associated with the medication such as headache, diarrhea, insomnia, depression,etc. Follow the instructions of the healthcare provider and do not exceed the recommended dose.Â
FAQs
What is Modvigil 200 mg?
Modvigil 200 mg is a wakefulness-promoting medication that is used to treat excessive daytime sleepiness.Â
What is the duration of action of Modafinil?
The duration of action of Modafinil is 10-12 hours.Â
What is the typical dosage of Modvigil 200 mg?
The general dosing of Modvigil 200 mg is 200 mg to be taken once daily.Â
How does Modvigil 200 mg work?
Modvigil 200 mg works by modulating neurotransmitters in the brain including dopamine, histamine, orexin, etc.Â
What are the side effects of Modvigil 200 mg?
The side effects of Modvigil 200 mg are headaches, nausea, dizziness, anxiety and insomnia.Â
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