DESCRIPTION
Modalert 200 mg is used to treat Obstructive sleep apnea, Narcolepsy and Shift Worker Sleep Disorder. It also has cognitive enhancing properties and can aid in increased focus, alertness and productivity. Modalert 200 mg consists of Modafinil which is a Central Nervous System (CNS) stimulant. It works by stimulating the brain to increase the physical and mental processes of the body.Â
Mechanism of action of Modalert 200 mg:
- Modafinil binds to the dopamine transporter (DAT) and blocks dopamine reuptake which boosts alertness.Â
- Modafinil stimulates the release of norepinephrine, serotonin and histamine along with wakefulness promoting orexin neurons. Orexin neurons are critical peptides that regulate the sleep-wake cycle.
- Modafinil inhibits GABA (gamma-aminobutyric acid), the main inhibitory neurotransmitter in the brain.Â
ADDITIONAL INFORMATION
Key Features
| About Modalert 200 mg | |
| Drug class: Central Nervous system Stimulant | |
| Sub class:Â Â Non-amphetamine wake-promoting agent |
| Product details | |
| Active Ingredient | Armodafinil |
| Inactive Ingredients | Lactose Monohydrate
Microcrystalline cellulose Croscarmellose sodium Povidone Magnesium stearate Pregelatinized starch |
| Packaging type | Blister |
| Pack size | 10*10 |
| Dosage | 200 mg |
| Used for | Excessive sleep disorder |
| Onset of action | 30 to 60 minutes |
| Duration of action | 10 to 12 hours |
| Manufacturer | Sun Pharmaceuticals Pvt Ltd |
| Shelf life | 24 months after the manufacturing date |
| Storage | Store at room temperature away from sunlight and moisture |
USAGE
Modalert 200 mg is used for:
- Narcolepsy
- Shift worker sleep disorder
- Obstructive sleep apnea
Off-label uses:
- Cognitive enhancement
- Chronic fatigue
- Major depressive disorder (MDD)
- Attention Deficit Hyperactivity Disorder (ADHD)
DOSAGE
The usual modafinil dosage is 200 mg daily.Â
For Narcolepsy & Shift worker Sleep Disorder: The medication is taken once in the morning to manage excessive sleepiness.Â
For Shift worker Sleep Disorder: The medication is generally taken an hour before the shift.Â
Avoid administration later in the day as it can lead to insomnia.Â
SIDE EFFECTS
Common side effects are:
- Nervous system: Headache, dizziness
- Gastrointestinal issues: Nausea, diarrhea, stomach pain, dry mouth, constipation
- Sleep disturbances: Insomnia or trouble falling asleep
- Other: Decreased appetite, thirst and excessive sweating
Serious side effects are:
- Severe skin reactions: Rashes, blisters, peeling skin or mouth sores
- Allergic reactions: Swelling of face, lips, tongue or difficulty in breathing
- Psychiatric effects: Anxiety, depression, hallucinations and suicidal thoughts
- Cardiovascular issues: Chest pain, irregular or pounding heartbeat
Interactions
Drug-drug Interactions
- Modafinil can make hormonal contraceptives less effective and increase the risk of pregnancy.Â
- Drugs like omeprazole, diazepam and phenytoin may stay in the system longer due to modafinil and increase the risk of toxicity and severe side effects.Â
- Modafinil when combined with opioids can lower their blood levels and lead to extreme pain.Â
- Modafinil can interact with medications like SSRIs e.g. citalopram.Â
- Modafinil can affect the blood levels of anticoagulants like warfarin making it less effective.Â
- Coadministration of Modafinil 200 mg with Citalopram can increase the risk of an irregular heartbeat.Â
Drug-Food Interactions
- Grapefruit or grapefruit juice should be avoided with modalert 200 mg as it can increase the level of modafinil in the body.Â
- Caffeine is also a Central Nervous system stimulant and combining it with Armodafinil can lead to additive effects.Â
- Concomitant use of alcohol and modafinil tablets can increase the risk of serious side effects.Â
Precautions & Warnings
- Do not administer the medication too late in the day as it can lead to insomnia.Â
- Avoid self-administration.
- Do not use the medication if you are allergic to Modafinil or any other component of the medication.Â
- Do not exceed the recommended dose.Â
- Use the medication with caution as there is a risk of misuse and dependency if taken in higher doses.Â
- Use with caution if you have a history of depression, mania or anxiety.Â
- Avoid alcohol consumption when using this medication as it can increase the risk of dizziness.Â
- Do not drive or operate heavy and hazardous machineries.Â
CONCLUSION
Modalert 200 mg is a wakefulness-promoting drug containing Modafinil 200 mg used for the treatment of excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Modafinil has a risk of abuse and overdose and should be used under the supervision of a healthcare professional.Â
FAQS
What is Modalert 200 mg?
Modalert 200 mg is a wakefulness promoting medication that helps with narcolepsy, shift worker sleep disorder and sleep apnea.Â
What are the side effects of modafinil?
The side effects of modafinil are headache, dizziness, nausea, anxiety, nervousness, etc.Â
Is Modalert 200 mg an addictive medication?
Modalert 200 mg can be addictive if used more than the recommended doses.Â
Does Modalert 200 mg cause diarrhea?
Yes. Modalert 200 mg can cause diarrhea.Â
Can alcohol be consumed with Modalert 200 mg?
No. Do not consume alcohol with Modalert 200 mg as it can increase the risk of side effects.Â
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