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DESCRIPTION
Waklert 150 mg is an Eugeroic, wakefulness promoting medicine which is used in dealing with Excessive daytime sleepiness (EDS), shift work sleep disorder (SWSD) and obstructive sleep apnea. It may contain armodafinil as an active ingredient. Waklert doesn’t dump dopamine like Adderall. It may work more selectively.
Waklert 150 mg may works by:
- It may block the DAT transporter as more dopamine stays in the synapse, especially in the hypothalamus. This may increase the alertness and motivation.
- Orexin which is the brain chemical that helps in awakening, Hypocretin system may get activated, this may boost orexin neurons in the lateral hypothalamus.
- There can be increase in histamine release in the tuberomammillary nucleus.
- There can be seen increase in excitatory glutamate and reduction in inhibitory GABA certain brain areas, this may lead to more mental activation.
- Norepinephrine may help in maintaining focus and attention.
ADDITIONAL INFORMATION
Key Features
| Â About (Waklert 150 mg) |
| Drug Class: Central Nervous System Stimulant |
| Subclass: Non-amphetamine wake-promoting agent |
| Â Product Details | |
| Composition | Active ingredients: Armodafinil Inactive ingredients: Croscarmellose sodium lactose monohydrate Magnesium stearate Colloidal Silicon dioxide Microcrinolose |
| Packaging Type | Blister |
| Pack Size | 10*10 |
| Dosage | 150 mg |
| Therapeutic class | Psychostimulant |
| Action Class | Dopamine reuptake inhibitor |
| Chemical class | Benzhydrylsulfinylacetamide derivative |
| Shelf Life | 36 months after the date of manufacturing |
| Usages | Treating symptoms of Narcolepsy, Shift-work Disorder, and Obstructive Sleep Apnea |
| Storage | Store at room temperature, 15°C to 30°C, away from moisture and sunlight. |
USAGE
Waklert 150 mg can be used in dealing with Excessive Daytime Sleepiness (EDS) and issues like:
- Obstructive sleep Apnea (OSA)
- Shift Work Sleep Disorder (SWSD)
DOSAGE
- It can be taken with food to avoid stomach upset and it can be taken once a day in the morning for normal shift work.
- It can be taken 1-hour prior shift work sleep disorder.
SIDE EFFECTS
- Headache
- Nausea
- Dry mouth
- Dizziness
- Insomnia
- Anxiety
- Loss of appetite
Interaction
- It may interact with hormonal contraceptives and may induces CYP3A4 that breaks down estrogen and progesterone faster.
- It may interact with Warfarin, Phenytoin this may lead to various side effects that may vary from individual to individual.
- It may can interact with benzodiazepines, cyclosporine and statins.
- It may also show interaction with caffeine and other stimulant so it should be avoided.
- It may can interact with alcohol so it should also be avoided.
Pharmacokinetics
- It may reach at peak plasma concentration in just 2 hours.
- Food may delay the absorption but doesn’t reduce the absorption.
- It binds to approx. 60% to plasma proteins.
- It is primarily metabolised in the liver via CYP3A4 and CYP3A5.
- The half life is about 15 hours.
Precautions
- If you are with prior history of ventricular hypertrophy, mitral valve prolapses and chest pain then it should be avoided.
- Pregnant and lactating women should avoid taking any such medications.
- Caffeine should be avoided while taking any such medications.
- If you allergic to modafinil or armodafinil then this medication should be avoided.
CONCLUSION
Waklert is the best and effective wakefulness pill that helps in dealing with narcolepsy, obstructive sleep apnea and shift work sleep disorder. It may work by blocking the DAT transporter as more dopamine stays in the synapse, especially in the hypothalamus. This may increase the alertness and motivation. It may show some side effects like headache, nausea, dry mouth, dizziness, insomnia etc this side effects may can vary from individual to individual. Prior taking any such medications consult to healthcare provider avoid any unwanted interactions.
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