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Armodacare 150 mg US To US

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DESCRIPTION

How does Armodacare 150 mg work?

R-enantiomer of modafinil, armodafinil is the longer-lasting R-enantiomer of modafinil. It has a longer half-life.
Dopamine & orexin systems, it increases dopamine in the brain by binding to the dopamine transporter and inhibiting reuptake. It also activates orexin neurons in the hypothalamus, which regulate wakefulness.
Histamine & GABA as it may increase histamine and decrease GABA, promoting alertness without the jittery ‘high’ of classic stimulants.
Improves wakefulness, alertness, and cognitive function in people with sleep disorders. It does NOT cure the disorder it manages symptoms.

ADDITIONAL INFORMATION

Key Features

About (Armodacare 150 mg)

Drug Class: Central Nervous System Stimulant

Subclass: Non-amphetamine wake-promoting agent

Product Details
Composition	Active ingredients: Armodafinil 150 mg Inactive ingredients: Croscarmellose sodium lactose monohydrate Magnesium stearate Povidone
Packaging Type	Blister
Pack Size	10*10
Dosage	150 mg
Therapeutic class	Neuro CNS stimulant
Action Class	Eugeroic Agent
Chemical class	Diphenylmethane derivative
Manufacturer	Aurobindo Pharma limited and retailed by Careclub pharmaceuticals LLP
Shelf Life	24-36 months after the date of manufacturing
Usages	Treating symptoms of Narcolepsy, Shift-work Disorder, and Obstructive Sleep Apnea
Country of Origin	India
Storage	Store at room temperature, 20°C to 25°C, away from moisture and sunlight.

USAGE

In the condition of Narcolepsy, it is used in reducing excessive daytime sleepiness.
Obstructive Sleep Apnea (OSA) is for residual sleepiness despite CPAP use.
In the case of Shift Work Sleep Disorder (SWSD) it can be used in promoting wakefulness during work shifts in people who work non-traditional hours

DOSAGE

In the condition of Narcolepsy & Obstructive Sleep Apnea (OSA) 150 mg to 250 mg it can be taken once a day in the morning.
Shift Work Disorder it can be taken 150 mg Once day approx. 1 hour before work shift.
Start dose can be 150 mg once a day.
It can be extended up to 250 mg/day only after consulting your healthcare provider.
It can be taken with or without food as absorption is not affected much by food, but high-fat meals may delay onset by 1 hour.

SIDE EFFECTS

Headache
Nausea
Dizziness
Insomnia
Anxiety
Dry mouth
Depression
Mania
Hallucinations
Suicidal thoughts
Chest pain
Increased heart rate/BP

Interactions

Armodafinil affects CYP3A4/5 and CYP2C19 enzymes resulting in side effects.
Hormonal contraceptives can reduce effectiveness of birth control pills, patches, rings. Use backup methods for 1 month after stopping
Cyclosporine levels may get decreased so it should be avoided.
Midazolam, triazolam levels gets decreased due to CYP3A4 induction.
Warfarin, phenytoin, diazepam levels may increase due to CYP2C19 inhibition this also can lead to severe side effects.
CYP3A4 inhibitors like ketoconazole, may increase armodafinil levels.
Alcohol may worsen side effects like dizziness so it should be avoided.

Pharmacokinetics

It may reach the Peak plasma concentration in just 2-4 hours after oral dose.
Half-life is about15 hours, which is longer than modafinil’s 12-15 hours.
Metabolism through Liver, via CYP3A4/5 and CYP2C19.
Excretion, mainly urine as metabolites.
Onset, Wakefulness effects usually within 1-2 hours.

Precautions & Warnings

Cardiovascular: Use caution if you have history of MI, unstable angina, recent heart attack, or uncontrolled hypertension. Check BP before starting
Psychiatric: May worsen anxiety, psychosis, mania. Screen for bipolar disorder first
Pregnancy: Category C. May cause fetal harm. Avoid unless benefits outweigh risks. Talk to your OB-GYN
Lactation: Not known if excreted in milk. Avoid breastfeeding
Dependence: Has potential for abuse. Don’t share your meds
Driving: May impair judgment. Avoid driving until you know how it affects you
Not a substitute: For OSA, continue CPAP. Armodafinil treats sleepiness, not the airway obstruction

CONCLUSION

Armodacare 150 mg is a wakefulness-promoting drug and nootropics used for excessive daytime sleepiness conditions like Shift work Sleep Disorder (SWSD), Narcolepsy and Obstructive Sleep Apnea (OSA). It may work by increases dopamine in the brain by binding to the dopamine transporter and inhibiting reuptake. It also activates orexin neurons in the hypothalamus, which regulate wakefulness. It may have some side effects like headache, nausea, dizziness, insomnia, anxiety, dry mouth, depression, mania and hallucinations. This side effects may can vary, to avoid such interactions consult prior your doctor or healthcare provider.

FAQS

What for Armodacare 150 mg is used?
Armodacare 150 mg can be used in treating symptoms of Shift work Sleep Disorder (SWSD), Narcolepsy and Obstructive Sleep Apnea (OSA).

What can be the possible side effects of Armodacare 150 mg?
The possible side effects of Armodafinil 150 mg can be headache, nausea, dizziness, insomnia, anxiety, dry mouth, depression, mania and hallucinations.

Who should avoid taking Armodacare 150 mg?
Pregnant and breast-feeding women and the one with prior medical conditions like heart, kidney and psychotic condition should avoid taking any such medications.

Is Armodacare 150 mg safe in pregnancy?
No, Armodacare 150 mg is not safe in pregnancy.

Is armodafinil can be used in treating depression?
Armodafinil may help in dealing with specific depression symptoms like fatigue, but doesn’t helps in treating depression fully.