DESCRIPTION
Modafinil containing Modacare 200 mg is a Central Nervous System (CNS) wakefulness promoting medication that may contain active ingredient as Modafinil and is used to treat excessive sleepiness associated with Narcolepsy, Obstructive sleep Apnea (OSA), and shift-work disorder (SWD).
It works by enhancing the level of dopamine and other neurotransmitters as:
- Modafinil inhibits sleep-inducing factors such as adenosine, this may promote wakefulness.
- There’s increase in the levels of neurotransmitters like dopamine, norepinephrine, and histamine which improve alertness and concentration.
- Manages excessive sleepiness modafinil is used to treat conditions such as narcolepsy, shift work sleep disorder, and obstructive sleep Apnea.
ADDITIONAL INFORMATION
Key Features
| Â About (Modacare 200 mg) |
| Drug Class: Central Nervous System Stimulant |
| Subclass: Non-amphetamine wake-promoting agent |
Additional Information
| Product Details | |
| Composition | Active ingredients:
Inactive ingredients:
|
| Packaging Type | Blister |
| Pack Size | 10*10 |
| Dosage | 200 mg |
| Therapeutic class | Central Nervous System Stimulant |
| Action Class | CNS Stimulant (non-amphetamine type) |
| Chemical class | Benzhydrylsulfinylacetamide derivative |
| Retailed by | Careclub |
| Shelf Life | 2-4 years after the date of manufacturing |
| Usages | Treating symptoms of Narcolepsy, Shift-work Disorder, and Obstructive Sleep Apnea |
| Country of Origin | India |
| Storage | Store at room temperature, 15°C to 30°C, away from moisture and sunlight. |
USAGE
Modacare 200 mg can be used in treating:
- Shift Work Sleep Disorder (SWSD)
- Narcolepsy
- Obstructive Sleep Apnea (OSA)
- Attention Deficit Hyperactivity Disorder (ADHD)
- Cognitive enhancement
DOSAGE
It can be taken once a day with or without food. Dosage may can vary from person to person so prior consult your medical professional.
- Starting Dose can be 100 mg once a day and it may be adjusted and extended up-to 200 mg according to individual requirement and tolerance.
- Maximum Dose can be 200 mg/day (usually split into morning and noon doses to avoid insomnia).
SIDE EFFECTS
- Dizziness
- Insomnia
- Diarrhea
- Back pain
- Runny nose
- Loss of appetite
- Headache
- Nausea
- Anxiety
- Anaphylaxis
- Hallucinations
- Stevens-Johnson Syndrome Angioedema
- Aggression, suicidal thoughts, mania
- Palpitations
- Hypertension
- Multiorgan hypersensitivity reactions
InteractionsÂ
- Modacare 200 mg may interact with CYP3A4, oral contraceptives, Cyclosporine, Midazolam, Triazolam, opioids like codeine, fentanyl hydrocodone and increase the risk of side effects.
- It may interact with Sofosbuvir and modafinil may reduce the plasma levels.
- Rifampin, Phenytoin, St. John’s Wort, Efavirenz may increase rate of metabolism.
- Ketoconazole, Itraconazole may inhibits metabolism that increase levels.
- It may show interactions with alcohol.
Pharmacokinetics
- Absorption:  Rapid absorption following oral administration; maximum plasma concentration within 2 – 4.
- Metabolism: Liver enzymes CYP3A4 (major), as well as CYP1A2.
- Half-Life: Average 15 hours (range 9 to 21 hours), longer in liver impairment.
Precautions
- The one with Cardiac condition, cardiac disease or hypertension should avoid such medications. Psychiatric history like Risk of mania, psychosis, or suicidal ideation monitor mood changes should avoid such medications.
- Renal Impairment: Dose adjustments are usually not required, although cases of severe renal impairment require close attention.
- It should be avoided in pregnancy and breast feeding.
- Avoid alcohol consumption while taking any such medications.
CONCLUSION
Modafinil containing Modacare 200 mg is a highly effective and safe Alertness-enhancing medication or vigilance promoting drug that is used in treating symptoms of narcolepsy, shift work disorder, and obstructive sleep apnea. It works by enhancing dopamine inhibition and other neurotransmitters inhibition with no or minimal side effects. While generally it is well-tolerated, dosage may vary from person to person according to their requirement and tolerance and side effects may also vary, for safer side always consult a healthcare provider prior using any of above medicines.
FAQS
Is Modacare 200 mg is used in dealing depression?
Modacare 200 mg is used in treating symptoms of narcolepsy, Shift-work Disorder, and Obstructive sleep Apnea. Modacare 200 mg does not cure depression but psychiatrists may prescribe them in fatigue, sleepiness, or lack of motivation.
How does Modacare 200 mg work?
Modacare 200 mg may boosts wakefulness by blocking dopamine reuptake and activates orexin neurons in your brain. This may promote alertness and help in getting over sleepiness.
Who should avoid taking Modacare 200 mg?
The one with prior psychotic history or heart, kidney condition and women in pregnancy and breast feeding should avoid taking Modacare 200 mg.
Is it safe to consume alcohol while taking Modacare 200 mg?
No, consuming alcohol while taking Modacare 200 mg may increase the risk of side effects so it should be avoided.
How to take Modacare 200 mg?
Modacare 200 can be take once a day in the morning, with or without food.
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